Control-Charting Automated Laboratory Instruments When Many Successive Differences May Be Zero

Article

Ciminera, Joseph L.; Tukey, John W.   (1989, ASQC)   Merck Sharp and Dohme Research Laboratories; Princeton University

Journal of Quality Technology    Vol. 21    No. 1
QICID: 5618    January 1989    pp. 7-15
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Article Abstract

There is a need to monitor automated instruments used in the routine daily assay of body fluid samples from a clinical laboratory. The usual procedure is to prepare and make use of quality control charts for calibrations using purchased standard body fluids. These calibrations are dispersed within each batch of analytical samples. However, because of nonstandard conditions and other vagaries that occur with this type of measurement, ordinary quality control chart procedures may not be satisfactory. Clifford's scheme using absolute values of successive differences is modified to be effective when a large fraction of such differences are zero. The modification should be effective in other circumstances where successive zero differences are a problem.

Keywords

Calibration,Automation,Control charts,Statistical methods,Fractional factorials


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